News

November 9, 2020November 9, 2020

1st Patient Dosed in Phase 1/2 Trial Testing CAR T-cell Therapy MB-102 in AML

News

The first patient has been dosed in an open-label Phase 1/2 clinical trial evaluating the safety and efficacy of MB-102 — a CD123-targeted CAR T-cell therapy — in adults ... Read more

November 5, 2020November 5, 2020

Complete Remission Reported in Patient in Ongoing Trial of APVO436

News

Aptevo Therapeutics’ investigational therapy APVO436 resulted in a patient’s complete disease remission in an ongoing trial in people with relapsed or refractory acute myeloid leukemia (AML) and high-grade myelodysplastic syndrome (MDS), the company ... Read more

October 29, 2020October 29, 2020

Dosing Begins in Phase 1 Trial Testing PRT1419 for Advanced AML, Other Blood Cancers

News

The first patient has been dosed in a Phase 1 trial testing the investigational cancer therapy PRT1419 in patients with relapsed or refractory blood cancers, including acute myeloid leukemia (AML), ... Read more

October 22, 2020October 22, 2020

FDA Approves Venclexta Combinations for Newly Diagnosed AML

News

The U.S. Food and Drug Administration (FDA) has granted full approval to Venclexta (venetoclax), in combination with Vidaza (azacitidine), Dacogen (decitabine), or low-dose cytarabine, for treating newly diagnosed adults ... Read more

October 19, 2020October 19, 2020

Telehealth ‘Helpful’ Alternative to In-person Care, Rare Disease Patients Say

News, syndicated

A majority of rare disease patients using telehealth during the COVID-19 pandemic thought the experience positive, and many would like the option of continuing its use in future appointments, a ... Read more

October 15, 2020October 15, 2020

Omidubicel Shows Further Trial Benefits for Marrow Transplants in AML, Other Cancers

News

Omidubicel, an experimental cell therapy for blood cancer patients needing a bone marrow transplant, is superior to standard umbilical cord blood transplant at increasing the proportion of patients achieving normal platelet counts ... Read more

October 12, 2020October 12, 2020

TXNIP Protein Deficiency Linked to Poor Prognosis for AML Patients, Study Finds

News

Low expression levels of the protein TXNIP — thioredoxin interacting protein — was associated with worse outcomes in people with acute myeloid leukemia (AML), according to the results of ... Read more

October 8, 2020October 8, 2020

Phase 1 Trial Finishes Dosing 1st AML Patient Group With Actimab-A Plus Venclexta

News

The first group of patients with relapsed or refractory acute myeloid leukemia (AML) has been dosed in a Phase 1/2 dose-escalation trial assessing the safety and efficacy of Actimab-A and Venclexta ... Read more

October 1, 2020October 1, 2020

‘Find the Right Fit’ Aims to Educate, Support People With Secondary AML

News

Jazz Pharmaceuticals, with help from the Myelodysplastic Syndrome (MDS) Foundation and the Cancer Support Community, has launched Find the Right Fit, an initiative providing educational resources about MDS and ... Read more

September 28, 2020September 28, 2020

First Clinical Trial Launched for AML, Other Blood Cancer Patients With COVID-19

News

The Leukemia & Lymphoma Society (LLS) has announced the launch of the first clinical trial dedicated to people with blood cancers, including acute myeloid leukemia (AML), who are infected with COVID-19. The ... Read more